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Mutation:
TP53 D281K
Summary
Isoform:
Position:
281
Ref:
D
Mutation:
K
PTM impact:
network-rewiring
PTM affected:
1
Kinases:
AURKB
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 284T
Affected site:
Position: 284
Residue: T
Type: phosphorylation
Best gain of PTM site:
CHEK1 (probability p=0.953)
Site: 284T (phosphorylation)
Position in motif: -3
There is 1 other predicted
gain:
- PAK1 (p=0.853)
Other known mutations affecting this site
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