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After several years of serving the research community, our ActiveDriverDB database will be retired on May 1st 2026. Please make sure to download any data you need and update your links or workflows before that date.

We want to sincerely thank all our users for their support, feedback, and collaboration over the years — your contributions have been invaluable to this project. A special thank you to Dr. Michal Krassowski for leading the development of our open-source software and database.

For any questions or assistance, please contact Jüri Reimand (juri.reimand@utoronto.ca).

You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020

Gene lists

You can browse genes and statistics for their primary isoforms by following lists, generated with ActiveDriver software.
Name Genes count
Clinical (ClinVar, excluding somatic): all sites 701
Clinical (ClinVar, excluding somatic): acetylation sites 45
Clinical (ClinVar, excluding somatic): glycosylation sites 26
Clinical (ClinVar, excluding somatic): methylation sites 70
Clinical (ClinVar, excluding somatic): phosphorylation sites 429
Clinical (ClinVar, excluding somatic): phosphorylation (SARS-CoV-2) sites 2
Clinical (ClinVar, excluding somatic): succinylation sites 2
Clinical (ClinVar, excluding somatic): sumoylation sites 17
Clinical (ClinVar, excluding somatic): ubiquitination sites 308
Cancer (TCGA PanCancerAtlas): all sites 2841
Cancer (TCGA PanCancerAtlas): acetylation sites 69
Cancer (TCGA PanCancerAtlas): glycosylation sites 29
Cancer (TCGA PanCancerAtlas): methylation sites 177
Cancer (TCGA PanCancerAtlas): phosphorylation sites 1857
Cancer (TCGA PanCancerAtlas): phosphorylation (SARS-CoV-2) sites 2
Cancer (TCGA PanCancerAtlas): succinylation sites 3
Cancer (TCGA PanCancerAtlas): sumoylation sites 52
Cancer (TCGA PanCancerAtlas): ubiquitination sites 978
Cancer (PCAWG): all sites 1592
Cancer (PCAWG): acetylation sites 26
Cancer (PCAWG): glycosylation sites 5
Cancer (PCAWG): methylation sites 30
Cancer (PCAWG): phosphorylation sites 872
Cancer (PCAWG): phosphorylation (SARS-CoV-2) sites 1
Cancer (PCAWG): succinylation sites 0
Cancer (PCAWG): sumoylation sites 26
Cancer (PCAWG): ubiquitination sites 563

Alternatively, you can browse a list of all genes.