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Mutation:
MSH6 A37T
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
Hereditary nonpolyposis colorectal neoplasms
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 33R
Affected site:
Position: 33
Residue: R
Type: methylation
Impact:
distalOther known mutations affecting this site
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Mutation | In sequence | Distance | Impact |
---|---|---|---|
33S | RASREGG[R/S]RAAAAPGA | 0 |
direct
|
33C | RASREGG[R/C]RAAAAPGA | 0 |
direct
|
33P | RASREGG[R/P]RAAAAPGA | 0 |
direct
|
33L | RASREGG[R/L]RAAAAPGA | 0 |
direct
|
32C | RASREG[G/C]GRAAAAPGA | 1 |
proximal
|
PTM Site: 41S
Affected site:
Position: 41
Residue: S
Type: phosphorylation, phosphorylation (SARS-CoV-2)
Impact:
distalOther known mutations affecting this site
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Mutation | In sequence | Distance | Impact |
---|---|---|---|
41Y | AAAAPGA[S/Y]SPSPGGDA | 0 |
direct
|
41C | AAAAPGA[S/C]SPSPGGDA | 0 |
direct
|
41F | AAAAPGA[S/F]SPSPGGDA | 0 |
direct
|
40T | AAAAPG[A/T]ASPSPGGDA | 1 |
proximal
|
40P | AAAAPG[A/P]ASPSPGGDA | 1 |
proximal
|
PTM Site: 43S
Affected site:
Position: 43
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
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Mutation | In sequence | Distance | Impact |
---|---|---|---|
43P | AAPGASP[S/P]SPGGDAAW | 0 |
direct
|
43F | AAPGASP[S/F]SPGGDAAW | 0 |
direct
|
42A | AAPGAS[P/A]PSPGGDAAW | 1 |
proximal
|
42S | AAPGAS[P/S]PSPGGDAAW | 1 |
proximal
|
42L | AAPGAS[P/L]PSPGGDAAW | 1 |
proximal
|
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