You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020

Summary

Isoform:
Position:
37
Ref:
A
Mutation:
T
PTM impact:
distal
PTM affected:
3
Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

Hereditary nonpolyposis colorectal neoplasms

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 33R

Affected site:

Position: 33
Residue: R
Type: methylation

Impact:

distal

Other known mutations affecting this site

Loading, please wait...
Mutation
In sequence
Distance
Impact
33S RASREGG[R/S]RAAAAPGA 0
direct
33C RASREGG[R/C]RAAAAPGA 0
direct
33P RASREGG[R/P]RAAAAPGA 0
direct
33L RASREGG[R/L]RAAAAPGA 0
direct
32C RASREG[G/C]GRAAAAPGA 1
proximal
Showing 1 to 5 of 32 rows

PTM Site: 41S

Affected site:

Position: 41
Residue: S
Type: phosphorylation, phosphorylation (SARS-CoV-2)

Impact:

distal

Other known mutations affecting this site

Loading, please wait...
Mutation
In sequence
Distance
Impact
41Y AAAAPGA[S/Y]SPSPGGDA 0
direct
41C AAAAPGA[S/C]SPSPGGDA 0
direct
41F AAAAPGA[S/F]SPSPGGDA 0
direct
40T AAAAPG[A/T]ASPSPGGDA 1
proximal
40P AAAAPG[A/P]ASPSPGGDA 1
proximal
Showing 1 to 5 of 34 rows

PTM Site: 43S

Affected site:

Position: 43
Residue: S
Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Loading, please wait...
Mutation
In sequence
Distance
Impact
43P AAPGASP[S/P]SPGGDAAW 0
direct
43F AAPGASP[S/F]SPGGDAAW 0
direct
42A AAPGAS[P/A]PSPGGDAAW 1
proximal
42S AAPGAS[P/S]PSPGGDAAW 1
proximal
42L AAPGAS[P/L]PSPGGDAAW 1
proximal
Showing 1 to 5 of 34 rows

If you have any questions or feedback about this mutation:

Contact us