You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020
Mutation:
MSH6 G45S
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
Hereditary nonpolyposis colorectal neoplasms
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 41S
Affected site:
Position: 41
Residue: S
Type: phosphorylation (SARS-CoV-2), phosphorylation
Impact:
distalOther known mutations affecting this site
Loading, please wait...
Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 41Y | AAAAPGA[S/Y]SPSPGGDA | 0 |
direct
|
| 41C | AAAAPGA[S/C]SPSPGGDA | 0 |
direct
|
| 41F | AAAAPGA[S/F]SPSPGGDA | 0 |
direct
|
| 40T | AAAAPG[A/T]ASPSPGGDA | 1 |
proximal
|
| 40P | AAAAPG[A/P]ASPSPGGDA | 1 |
proximal
|
PTM Site: 43S
Affected site:
Position: 43
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
Loading, please wait...
Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 43P | AAPGASP[S/P]SPGGDAAW | 0 |
direct
|
| 43F | AAPGASP[S/F]SPGGDAAW | 0 |
direct
|
| 42A | AAPGAS[P/A]PSPGGDAAW | 1 |
proximal
|
| 42S | AAPGAS[P/S]PSPGGDAAW | 1 |
proximal
|
| 42L | AAPGAS[P/L]PSPGGDAAW | 1 |
proximal
|
PTM Site: 51S
Affected site:
Position: 51
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
Loading, please wait...
Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 51G | PGGDAAW[S/G]SEAGPGPR | 0 |
direct
|
| 51I | PGGDAAW[S/I]SEAGPGPR | 0 |
direct
|
| 51R | PGGDAAW[S/R]SEAGPGPR | 0 |
direct
|
| 50R | PGGDAA[W/R]WSEAGPGPR | 1 |
proximal
|
| 50C | PGGDAA[W/C]WSEAGPGPR | 1 |
proximal
|
If you have any questions or feedback about this mutation:
Contact us