MSH6 P59T

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Mutation:

Summary

Isoform:

NM_001281492

Position:

Ref:

Mutation:

PTM impact:

distal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 63S

Affected site:

Position: 63

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

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Mutation	In sequence	Impact
63T	GPRPLAR[S/T]SASPPKAK	direct
63P	GPRPLAR[S/P]SASPPKAK	direct
63A	GPRPLAR[S/A]SASPPKAK	direct
63Y	GPRPLAR[S/Y]SASPPKAK	direct
63C	GPRPLAR[S/C]SASPPKAK	direct

Showing 1 to 5 of 36 rows

PTM Site: 65S

Affected site:

Position: 65

Residue: S

Type: phosphorylation, phosphorylation (SARS-CoV-2)

Impact:

distal

Other known mutations affecting this site

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Mutation	In sequence	Distance	Impact
65A	RPLARSA[S/A]SPPKAKNL	0	direct
65L	RPLARSA[S/L]SPPKAKNL	0	direct
64T	RPLARS[A/T]ASPPKAKNL	1	proximal
64P	RPLARS[A/P]ASPPKAKNL	1	proximal
64E	RPLARS[A/E]ASPPKAKNL	1	proximal

Showing 1 to 5 of 34 rows

External references

dbSNP:

rs761033647

If you have any questions or feedback about this mutation: