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CCNA2 (NM_001237) - cyclin A2

Cyclin-A2

Mutations Visualisation

Protein summary

This is preferred isoform of CCNA2 protein.
CCNA2: cyclin-A2
Description:

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M. [provided by RefSeq, Aug 2016]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

Evidence data:
Transcript exon combination :: SRR1163657.111004.1, SRR1163658.202233.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350]

##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000274026.10/ ENSP00000274026.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

Strand
-
Chromosome
4
Protein
432 residues
All mutations
52
PTM sites
16
CDS
122,738,792 - 122,744,783
Transcription
122,737,598 - 122,745,088
37.04% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 890
UniProt
Ensembl