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PKMYT1 (NM_004203) - protein kinase, membrane associated tyrosine/threonine 1
Membrane-Associated Tyrosine- And Threonine-Specific Cdc2-Inhibitory Kinase Isoform 1
Legend
Mutation impacts
direct
network-rewiring
motif-changing
proximal
distal
none
Sites
multiple types
acetylation
methylation
succinylation
sumoylation
ubiquitination
glycosylation
- C-linked
- N-linked
- O-linked
- S-linked
phosphorylation
- SARS-CoV-2
Others
Exact position of a PTM site
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Mutations Visualisation
Protein summary
This is preferred isoform of PKMYT1 protein.
View all 4 isoforms
PKMYT1:
membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform 1
Description:
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].
- Strand
- -
- Chromosome
- 16
- Protein
- 499 residues
- All mutations
- 92
- PTM sites
- 37
- CDS
- 3,022,953 - 3,029,658
- Transcription
- 3,022,791 - 3,030,540
External references
Mappings retrieved from NCBI & UniProt.