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NOC2L (NM_015658) - NOC2 like nucleolar associated transcriptional repressor

Nucleolar Complex Protein 2 Homolog

Mutations Visualisation

Protein summary

This is preferred isoform of NOC2L protein.
NOC2L: nucleolar complex protein 2 homolog
Description:

Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM, Mar 2008].

Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

Evidence data:
Transcript exon combination :: AK225239.1, AK024284.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350]

##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000327044.7/ ENSP00000317992.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

Strand
-
Chromosome
1
Protein
749 residues
All mutations
163
PTM sites
48
CDS
880,073 - 894,620
Transcription
879,582 - 894,679
33.24% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 26155
UniProt
Ensembl