After several years of serving the research community, our ActiveDriverDB database will be retired on May 1st 2026. Please make sure to download any data you need and update your links or workflows before that date.

We want to sincerely thank all our users for their support, feedback, and collaboration over the years — your contributions have been invaluable to this project. A special thank you to Dr. Michal Krassowski for leading the development of our open-source software and database.

For any questions or assistance, please contact Jüri Reimand (juri.reimand@utoronto.ca).

You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020

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You can provide a VCF file and plain-text mutation lines above at once, so result for both will be shown on one page.Stop codon mutations are not considered.Maximum 20 MB of upload is allowed.
* Mutations will be stored for 7 days. Ticking this box allows you to return to the results later easily.