Download input files of the ActiveDriver method

• Protein sequences
• Protein disorder
• Protein substitutions:
  • ESP6500 (for all isoforms)
  • ClinVar (for all isoforms)
  • TCGA (for all isoforms)
  • PCAWG (for all isoforms)
  • 1000 Genomes (for all isoforms)
• Protein PTM sites*
• Symbol to RefSeq mapping

Download entire datasets as ZIP files

1. All cancer (TCGA) mutations affecting PTM sites*
2. All cancer (PCAWG) mutations affecting PTM sites*
3. All disease mutations affecting PTM sites*
4. All population variants affecting PTM sites*
5. Site-specific network of kinases and targets*

 Or alternatively, download all the data for (1-5)* at once.

Download datasets with genomic coordinates

1. Cancer mutations affecting PTM sites (TCGA)*
2. Cancer mutations affecting PTM sites (PCAWG)*
3. All disease mutations affecting PTM sites*
4. Population variants affecting PTM sites (ESP6500)*
5. Population variants affecting PTM sites (1000 Genomes)*

The download data (especially those marked with *) are partially based on PhosphositePlus data and are not for commercial use.

Please see Terms and Conditions of PSP on the following page: Terms of Use and License.

This website was most recently updated on 15th March 2021.

For the data from the previous versions:

• v2020: please visit: activedriverdb.org/v2020/download/
• v2017: please visit: activedriverdb.org/v2017/download/

Download source code

The source code can be downloaded from the GitHub repository: github.com/reimandlab/ActiveDriverDB.

Use one of the following commands to download it quickly:

git clone https://github.com/reimandlab/ActiveDriverDB.git

wget https://github.com/reimandlab/ActiveDriverDB/archive/master.zip

Please, see README.md file for installation and deployment instructions. The database structure can be generated using source files linked above.