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Mutation:
DPYD C385S
Summary
Clinical Information
Cancer types: (TCGA MC3)
BLCA
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 381K
Affected site:
Position: 381
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 380G | PEEMEL[A/G]AKEEKCEFL | 1 |
proximal
|
| 378Q | PEEM[E/Q]ELAKEEKCEFL | 3 |
distal
|
| 377V | PEE[M/V]MELAKEEKCEFL | 4 |
distal
|
| 382D | PEEMELAK[E/D]EEKCEFL | 1 |
proximal
|
| 377I | PEE[M/I]MELAKEEKCEFL | 4 |
distal
|
| 383K | PEEMELAKE[E/K]EKCEFL | 2 |
proximal
|
| 385S | PEEMELAKEEK[C/S]CEFL | 4 |
distal
|
PTM Site: 384K
Affected site:
Position: 384
Residue: K
Type: acetylation, ubiquitination
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 380G | MEL[A/G]AKEEKCEFLPFL | 4 |
distal
|
| 378Q | M[E/Q]ELAKEEKCEFLPFL | 6 |
distal
|
| 382D | MELAK[E/D]EEKCEFLPFL | 2 |
proximal
|
| 383K | MELAKE[E/K]EKCEFLPFL | 1 |
proximal
|
| 385S | MELAKEEK[C/S]CEFLPFL | 1 |
proximal
|
| 388V | MELAKEEKCEF[L/V]LPFL | 4 |
distal
|
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