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Mutation:
PDE3A A571V
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0077]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 568T
Affected site:
Position: 568
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 569E | SHRALTYT[Q/E]QSAPDLS | 1 |
network-rewiring
|
| 571V | SHRALTYTQS[A/V]APDLS | 3 |
distal
|
| 572S | SHRALTYTQSA[P/S]PDLS | 4 |
distal
|
| 566S | SHRAL[T/S]TYTQSAPDLS | 2 |
proximal
|
| 565F | SHRA[L/F]LTYTQSAPDLS | 3 |
distal
|
| 573H | SHRALTYTQSAP[D/H]DLS | 5 |
distal
|
PTM Site: 570S
Affected site:
Position: 570
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 569E | RALTYT[Q/E]QSAPDLSPQ | 1 |
proximal
|
| 571V | RALTYTQS[A/V]APDLSPQ | 1 |
proximal
|
| 572S | RALTYTQSA[P/S]PDLSPQ | 2 |
proximal
|
| 566S | RAL[T/S]TYTQSAPDLSPQ | 4 |
distal
|
| 565F | RA[L/F]LTYTQSAPDLSPQ | 5 |
distal
|
| 573H | RALTYTQSAP[D/H]DLSPQ | 3 |
distal
|
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