You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020
Mutation:
S100A13 D64G
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0077]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 59K
Affected site:
Position: 59
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 64G | DVGSLDEKMKSL[D/G]DVN | 5 |
distal
|
| 54S | DV[G/S]GSLDEKMKSLDVN | 5 |
distal
|
| 54V | DV[G/V]GSLDEKMKSLDVN | 5 |
distal
|
| 56F | DVGS[L/F]LDEKMKSLDVN | 3 |
distal
|
PTM Site: 61K
Affected site:
Position: 61
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 66K | GSLDEKMKSLDV[N/K]NQD | 5 |
distal
|
| 64G | GSLDEKMKSL[D/G]DVNQD | 3 |
distal
|
| 56F | GS[L/F]LDEKMKSLDVNQD | 5 |
distal
|
PTM Site: 62S
Affected site:
Position: 62
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 66K | SLDEKMKSLDV[N/K]NQDS | 4 |
distal
|
| 64G | SLDEKMKSL[D/G]DVNQDS | 2 |
proximal
|
| 56F | S[L/F]LDEKMKSLDVNQDS | 6 |
distal
|
PTM Site: 69S
Affected site:
Position: 69
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 74H | SLDVNQDSELKF[N/H]NEY | 5 |
distal
|
| 66K | SLDV[N/K]NQDSELKFNEY | 3 |
distal
|
| 64G | SL[D/G]DVNQDSELKFNEY | 5 |
distal
|
| 74S | SLDVNQDSELKF[N/S]NEY | 5 |
distal
|
| 69W | SLDVNQD[S/W]SELKFNEY | 0 |
direct
|
If you have any questions or feedback about this mutation:
Contact us