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Mutation:
TMPO D185H
Summary
Isoform:
Position:
185
Ref:
D
Mutation:
H
PTM impact:
proximal
PTM affected:
4
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
BLCA
Cancer types: (PCAWG)
Bladder-TCC
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 180S
Affected site:
Position: 180
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 177G | RQNG[S/G]SNDSDRYSDNE | 3 |
distal
|
| 186S | RQNGSNDSDRYSD[N/S]NE | 6 |
distal
|
| 185H | RQNGSNDSDRYS[D/H]DNE | 5 |
distal
|
| 174H | R[Q/H]QNGSNDSDRYSDNE | 6 |
distal
|
PTM Site: 183Y
Affected site:
Position: 183
Residue: Y
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 177G | G[S/G]SNDSDRYSDNEEDS | 6 |
distal
|
| 186S | GSNDSDRYSD[N/S]NEEDS | 3 |
distal
|
| 185H | GSNDSDRYS[D/H]DNEEDS | 2 |
proximal
|
PTM Site: 184S
Affected site:
Position: 184
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 186S | SNDSDRYSD[N/S]NEEDSK | 2 |
proximal
|
| 185H | SNDSDRYS[D/H]DNEEDSK | 1 |
proximal
|
PTM Site: 190S
Affected site:
Position: 190
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 186S | YSD[N/S]NEEDSKIELKLE | 4 |
distal
|
| 185H | YS[D/H]DNEEDSKIELKLE | 5 |
distal
|
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