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Mutation:
BCLAF1 S177N
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0154]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 177S
Affected site:
Position: 177
Residue: S
Type: phosphorylation, phosphorylation (SARS-CoV-2)
Impact:
directOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 177N | EGEPQEE[S/N]SPLKSKSQ | 0 |
direct
|
| 171R | E[G/R]GEPQEESPLKSKSQ | 6 |
distal
|
PTM Site: 181S
Affected site:
Position: 181
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 187Q | QEESPLKSKSQEE[P/Q]PK | 6 |
distal
|
| 177N | QEE[S/N]SPLKSKSQEEPK | 4 |
distal
|
| 187L | QEESPLKSKSQEE[P/L]PK | 6 |
distal
|
| 184L | QEESPLKSKS[Q/L]QEEPK | 3 |
distal
|
PTM Site: 183S
Affected site:
Position: 183
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 187Q | ESPLKSKSQEE[P/Q]PKDT | 4 |
distal
|
| 177N | E[S/N]SPLKSKSQEEPKDT | 6 |
distal
|
| 189G | ESPLKSKSQEEPK[D/G]DT | 6 |
distal
|
| 187L | ESPLKSKSQEE[P/L]PKDT | 4 |
distal
|
| 184L | ESPLKSKS[Q/L]QEEPKDT | 1 |
network-rewiring
|
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