CSDE1 I500M

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Mutation:

Summary

Isoform:

NM_001130523

Position:

500

Ref:

Mutation:

PTM impact:

distal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

LUSC

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

[0.0077]

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 496T

Affected site:

Position: 496

Residue: T

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
500M	AKDVEGSTSPQ[I/M]IGDK	4	distal
492M	AKD[V/M]VEGSTSPQIGDK	4	distal
496A	AKDVEGS[T/A]TSPQIGDK	0	direct
491N	AK[D/N]DVEGSTSPQIGDK	5	distal

PTM Site: 497S

Affected site:

Position: 497

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
500M	KDVEGSTSPQ[I/M]IGDKV	3	distal
492M	KD[V/M]VEGSTSPQIGDKV	5	distal
496A	KDVEGS[T/A]TSPQIGDKV	1	proximal
491N	K[D/N]DVEGSTSPQIGDKV	6	distal

PTM Site: 503K

Affected site:

Position: 503

Residue: K

Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
508V	TSPQIGDKVEFS[I/V]ISD	5	distal
500M	TSPQ[I/M]IGDKVEFSISD	3	distal
509T	TSPQIGDKVEFSI[S/T]SD	6	distal

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