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Mutation:
GRIN2A S905F
Summary
Clinical Information
Cancer types: (TCGA MC3)
SKCM
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 900S
Affected site:
Position: 900
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 904F | NMLKLLRSAKN[I/F]ISSM | 4 |
distal
|
| 899W | NMLKLL[R/W]RSAKNISSM | 1 |
proximal
|
| 896E | NML[K/E]KLLRSAKNISSM | 4 |
distal
|
| 905F | NMLKLLRSAKNI[S/F]SSM | 5 |
distal
|
PTM Site: 905S
Affected site:
Position: 905
Residue: S
Type: phosphorylation
Impact:
directOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 904F | LRSAKN[I/F]ISSMSNMNS | 1 |
proximal
|
| 899W | L[R/W]RSAKNISSMSNMNS | 6 |
distal
|
| 905F | LRSAKNI[S/F]SSMSNMNS | 0 |
direct
|
| 910I | LRSAKNISSMSN[M/I]MNS | 5 |
distal
|
PTM Site: 906S
Affected site:
Position: 906
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 912C | RSAKNISSMSNMN[S/C]SS | 6 |
distal
|
| 904F | RSAKN[I/F]ISSMSNMNSS | 2 |
proximal
|
| 905F | RSAKNI[S/F]SSMSNMNSS | 1 |
proximal
|
| 910I | RSAKNISSMSN[M/I]MNSS | 4 |
distal
|
PTM Site: 908S
Affected site:
Position: 908
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 912C | AKNISSMSNMN[S/C]SSRM | 4 |
distal
|
| 904F | AKN[I/F]ISSMSNMNSSRM | 4 |
distal
|
| 905F | AKNI[S/F]SSMSNMNSSRM | 3 |
distal
|
| 910I | AKNISSMSN[M/I]MNSSRM | 2 |
proximal
|
PTM Site: 912S
Affected site:
Position: 912
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 918S | SSMSNMNSSRMDS[P/S]PK | 6 |
distal
|
| 917A | SSMSNMNSSRMD[S/A]SPK | 5 |
distal
|
| 915T | SSMSNMNSSR[M/T]MDSPK | 3 |
distal
|
| 912C | SSMSNMN[S/C]SSRMDSPK | 0 |
direct
|
| 910I | SSMSN[M/I]MNSSRMDSPK | 2 |
proximal
|
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