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Mutation:
MUC1 S234R
Summary
Isoform:
Position:
234
Ref:
S
Mutation:
R
PTM impact:
direct
PTM affected:
7
Kinases:
PDGFRB
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 229T
Affected site:
Position: 229
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 234R | DIFPARDTYHPM[S/R]SEY | 5 |
distal
|
| 226G | DIFP[A/G]ARDTYHPMSEY | 3 |
distal
|
| 226S | DIFP[A/S]ARDTYHPMSEY | 3 |
distal
|
PTM Site: 230Y
Affected site:
Position: 230
Residue: Y
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 234R | IFPARDTYHPM[S/R]SEYP | 4 |
distal
|
| 226G | IFP[A/G]ARDTYHPMSEYP | 4 |
distal
|
| 226S | IFP[A/S]ARDTYHPMSEYP | 4 |
distal
|
PTM Site: 234S
Affected site:
Position: 234
Residue: S
Type: phosphorylation
Impact:
directOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 234R | RDTYHPM[S/R]SEYPTYHT | 0 |
direct
|
PTM Site: 236Y
Affected site:
Position: 236
Residue: Y
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 234R | TYHPM[S/R]SEYPTYHTHG | 2 |
proximal
|
PTM Site: 238T
Affected site:
Position: 238
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 234R | HPM[S/R]SEYPTYHTHGRY | 4 |
distal
|
| 244C | HPMSEYPTYHTHG[R/C]RY | 6 |
distal
|
PTM Site: 239Y
Affected site:
Position: 239
Residue: Y
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 234R | PM[S/R]SEYPTYHTHGRYV | 5 |
distal
|
| 244C | PMSEYPTYHTHG[R/C]RYV | 5 |
distal
|
PTM Site: 241T
Affected site:
Position: 241
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 244C | SEYPTYHTHG[R/C]RYVPP | 3 |
distal
|
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