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Mutation:
CTNND1 Q200H
Summary
Isoform:
Position:
200
Ref:
Q
Mutation:
H
PTM impact:
proximal
PTM affected:
4
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0079]
Minor Allele Frequency: (1000 Genomes)
[0.0399361]
PTM Site: 194Y
Affected site:
Position: 194
Residue: Y
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 200H | YRPSMEGYRAPSR[Q/H]QD | 6 |
distal
|
| 195Q | YRPSMEGY[R/Q]RAPSRQD | 1 |
proximal
|
PTM Site: 195R
Affected site:
Position: 195
Residue: R
Type: methylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 200H | RPSMEGYRAPSR[Q/H]QDV | 5 |
distal
|
| 195Q | RPSMEGY[R/Q]RAPSRQDV | 0 |
direct
|
PTM Site: 198S
Affected site:
Position: 198
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 200H | MEGYRAPSR[Q/H]QDVYGP | 2 |
proximal
|
| 195Q | MEGY[R/Q]RAPSRQDVYGP | 3 |
network-rewiring
|
PTM Site: 203Y
Affected site:
Position: 203
Residue: Y
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 200H | APSR[Q/H]QDVYGPQPQVR | 3 |
distal
|
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