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Mutation:
PRKCQ K325E
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.059904200000000005]
PTM Site: 323S
Affected site:
Position: 323
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 329K | VEIGLPCSIKNEA[R/K]RP | 6 |
distal
|
| 325E | VEIGLPCSI[K/E]KNEARP | 2 |
proximal
|
| 324N | VEIGLPCS[I/N]IKNEARP | 1 |
proximal
|
| 321T | VEIGL[P/T]PCSIKNEARP | 2 |
proximal
|
| 319D | VEI[G/D]GLPCSIKNEARP | 4 |
distal
|
PTM Site: 325K
Affected site:
Position: 325
Residue: K
Type: ubiquitination
Impact:
directOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 330L | IGLPCSIKNEAR[P/L]PPC | 5 |
distal
|
| 329K | IGLPCSIKNEA[R/K]RPPC | 4 |
distal
|
| 325E | IGLPCSI[K/E]KNEARPPC | 0 |
direct
|
| 324N | IGLPCS[I/N]IKNEARPPC | 1 |
proximal
|
| 321T | IGL[P/T]PCSIKNEARPPC | 4 |
distal
|
| 319D | I[G/D]GLPCSIKNEARPPC | 6 |
distal
|
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