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Mutation:
STARD13 R33H
Summary
Isoform:
Position:
33
Ref:
R
Mutation:
H
PTM impact:
network-rewiring
PTM affected:
1
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0077]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 36S
Affected site:
Position: 36
Residue: S
Type: phosphorylation
Best loss of PTM site:
AKT1 (probability p=0.986)
Site: 36S (phosphorylation)
Position in motif: -3
There are 6 other predicted
losses:
- PAK1 (p=0.982)
- CAMK2G (p=0.899)
- CAMK2A (p=0.884)
- CAMK1 (p=0.877)
- PRKAA1 (p=0.871)
- PRKD1 (p=0.854)
Other known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 40N | QRTSRRWSRVD[D/N]DLYT | 4 |
distal
|
| 38M | QRTSRRWSR[V/M]VDDLYT | 2 |
proximal
|
| 33H | QRTS[R/H]RRWSRVDDLYT | 3 |
network-rewiring
|
| 31S | QR[T/S]TSRRWSRVDDLYT | 5 |
distal
|
| 37L | QRTSRRWS[R/L]RVDDLYT | 1 |
proximal
|
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