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Mutation:
STARD13 P54L
Summary
Isoform:
Position:
54
Ref:
P
Mutation:
L
PTM impact:
network-rewiring
PTM affected:
1
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
LUSC
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 53S
Affected site:
Position: 53
Residue: S
Type: phosphorylation
Best loss of PTM site:
MAPK14 (probability p=0.926)
Site: 53S (phosphorylation)
Position in motif: 1
There are 7 other predicted
losses:
- GSK3B (p=0.906)
- CDK1 (p=0.9)
- MAPK8 (p=0.899)
- MAPK1 (p=0.882)
- MAPK3 (p=0.876)
- CDK3 (p=0.874)
- CDK2 (p=0.869)
Other known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 57M | PRGDRNGSPGG[T/M]TGMR | 4 |
distal
|
| 51S | PRGDR[N/S]NGSPGGTGMR | 2 |
proximal
|
| 54L | PRGDRNGS[P/L]PGGTGMR | 1 |
network-rewiring
|
| 53L | PRGDRNG[S/L]SPGGTGMR | 0 |
direct
|
| 52V | PRGDRN[G/V]GSPGGTGMR | 1 |
proximal
|
| 47Q | P[R/Q]RGDRNGSPGGTGMR | 6 |
distal
|
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