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Mutation:
ANKRD11 P861L
Summary
Isoform:
Position:
861
Ref:
P
Mutation:
L
PTM impact:
network-rewiring
PTM affected:
2
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0077]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 857S
Affected site:
Position: 857
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 861L | FDFKGEDSWDS[P/L]PVTD | 4 |
distal
|
| 860L | FDFKGEDSWD[S/L]SPVTD | 3 |
distal
|
| 852L | FD[F/L]FKGEDSWDSPVTD | 5 |
distal
|
PTM Site: 860S
Affected site:
Position: 860
Residue: S
Type: phosphorylation
Only loss of PTM site:
CDK2 (probability p=0.886)
Site: 860S (phosphorylation)
Position in motif: 1
Other known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 861L | KGEDSWDS[P/L]PVTDYRD | 1 |
network-rewiring
|
| 860L | KGEDSWD[S/L]SPVTDYRD | 0 |
direct
|
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