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Mutation:
MPP2 G335S
Summary
Isoform:
Position:
335
Ref:
G
Mutation:
S
PTM impact:
proximal
PTM affected:
2
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0077]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 336S
Affected site:
Position: 336
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 335S | NSGTLC[G/S]GSLSGKKKK | 1 |
proximal
|
| 334R | NSGTL[C/R]CGSLSGKKKK | 2 |
network-rewiring
|
| 339E | NSGTLCGSLS[G/E]GKKKK | 3 |
network-rewiring
|
PTM Site: 338S
Affected site:
Position: 338
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 335S | GTLC[G/S]GSLSGKKKKRM | 3 |
distal
|
| 334R | GTL[C/R]CGSLSGKKKKRM | 4 |
distal
|
| 344Q | GTLCGSLSGKKKK[R/Q]RM | 6 |
distal
|
| 339E | GTLCGSLS[G/E]GKKKKRM | 1 |
proximal
|
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