RANGAP1 K178N

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Mutation:

Summary

Isoform:

NM_001278651

Position:

178

Ref:

Mutation:

PTM impact:

direct

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

LUAD

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 172K

Affected site:

Position: 172

Residue: K

Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
171Q	ALTECH[R/Q]RKSSAQGKP	1	proximal
168K	ALT[E/K]ECHRKSSAQGKP	4	distal
178N	ALTECHRKSSAQG[K/N]KP	6	distal
178R	ALTECHRKSSAQG[K/R]KP	6	distal
170L	ALTEC[H/L]HRKSSAQGKP	2	proximal

PTM Site: 178K

Affected site:

Position: 178

Residue: K

Type: ubiquitination

Impact:

direct

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
178N	RKSSAQG[K/N]KPLALKVF	0	direct
178R	RKSSAQG[K/R]KPLALKVF	0	direct

PTM Site: 183K

Affected site:

Position: 183

Residue: K

Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
185S	QGKPLALKV[F/S]FVAGRN	2	proximal
178N	QG[K/N]KPLALKVFVAGRN	5	distal
178R	QG[K/R]KPLALKVFVAGRN	5	distal

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