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Mutation:
HNRNPM G347S
Summary
Isoform:
Position:
347
Ref:
G
Mutation:
S
PTM impact:
proximal
PTM affected:
3
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0462]
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 340T
Affected site:
Position: 340
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 344V | SIERMGQTMER[I/V]IGSG | 4 |
distal
|
| 336P | SIE[R/P]RMGQTMERIGSG | 4 |
distal
|
| 337I | SIER[M/I]MGQTMERIGSG | 3 |
distal
|
PTM Site: 346S
Affected site:
Position: 346
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 347S | QTMERIGS[G/S]GVERMGA | 1 |
proximal
|
| 344V | QTMER[I/V]IGSGVERMGA | 2 |
proximal
|
| 351V | QTMERIGSGVER[M/V]MGA | 5 |
distal
|
| 350H | QTMERIGSGVE[R/H]RMGA | 4 |
distal
|
PTM Site: 350R
Affected site:
Position: 350
Residue: R
Type: methylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 347S | RIGS[G/S]GVERMGAGMGF | 3 |
distal
|
| 354S | RIGSGVERMGA[G/S]GMGF | 4 |
distal
|
| 344V | R[I/V]IGSGVERMGAGMGF | 6 |
distal
|
| 351V | RIGSGVER[M/V]MGAGMGF | 1 |
proximal
|
| 350H | RIGSGVE[R/H]RMGAGMGF | 0 |
direct
|
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