PTPN6 D59N

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Mutation:

Summary

Isoform:

NM_002831

Position:

Ref:

Mutation:

PTM impact:

proximal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

DLBC

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 57S

Affected site:

Position: 57

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
53W	THI[R/W]RIQNSGDFYDLY	4	distal
59N	THIRIQNSG[D/N]DFYDLY	2	proximal

PTM Site: 61Y

Affected site:

Position: 61

Residue: Y

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
59N	IQNSG[D/N]DFYDLYGGEK	2	proximal

PTM Site: 64Y

Affected site:

Position: 64

Residue: Y

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
59N	SG[D/N]DFYDLYGGEKFAT	5	distal

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