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Mutation:
SEMA3F R487H
Summary
Isoform:
Position:
487
Ref:
R
Mutation:
H
PTM impact:
network-rewiring
PTM affected:
1
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0077]
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 485T
Affected site:
Position: 485
Residue: T
Type: phosphorylation
Best loss of PTM site:
PRKCA (probability p=0.926)
Site: 485T (phosphorylation)
Position in motif: 2
There is 1 other predicted
loss:
- PRKCG (p=0.859)
Other known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 487H | YEVLFLGTD[R/H]RGTVQK | 2 |
network-rewiring
|
| 479K | Y[E/K]EVLFLGTDRGTVQK | 6 |
distal
|
| 488R | YEVLFLGTDR[G/R]GTVQK | 3 |
distal
|
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