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Mutation:
ABL1 T315I
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
Leukemia, Philadelphia chromosome-positive, resistant to imatinib
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 312Y
Affected site:
Position: 312
Residue: Y
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
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Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 312C | CTREPPF[Y/C]YIITEFMT | 0 |
direct
|
| 311L | CTREPP[F/L]FYIITEFMT | 1 |
proximal
|
| 313V | CTREPPFY[I/V]IITEFMT | 1 |
proximal
|
| 310T | CTREP[P/T]PFYIITEFMT | 2 |
proximal
|
| 310L | CTREP[P/L]PFYIITEFMT | 2 |
proximal
|
External references
dbSNP:
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