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Mutation:
ABL1 F311L
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
Chronic myelogenous leukemia, BCR-ABL1 positive
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 306T
Affected site:
Position: 306
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 311L | VQLLGVCTREPP[F/L]FYI | 5 |
distal
|
| 303R | VQLL[G/R]GVCTREPPFYI | 3 |
network-rewiring
|
| 310T | VQLLGVCTREP[P/T]PFYI | 4 |
distal
|
| 310L | VQLLGVCTREP[P/L]PFYI | 4 |
distal
|
| 312C | VQLLGVCTREPPF[Y/C]YI | 6 |
distal
|
PTM Site: 312Y
Affected site:
Position: 312
Residue: Y
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 311L | CTREPP[F/L]FYIITEFMT | 1 |
proximal
|
| 315I | CTREPPFYII[T/I]TEFMT | 3 |
distal
|
| 310T | CTREP[P/T]PFYIITEFMT | 2 |
proximal
|
| 310L | CTREP[P/L]PFYIITEFMT | 2 |
proximal
|
| 313V | CTREPPFY[I/V]IITEFMT | 1 |
proximal
|
| 312C | CTREPPF[Y/C]YIITEFMT | 0 |
direct
|
External references
dbSNP:
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