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Mutation:
NT5C2 V512L
Summary
Clinical Information
Cancer types: (TCGA MC3)
UCEC
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 510T
Affected site:
Position: 510
Residue: T
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 510P | PLATRNR[T/P]TSVDFKDT | 0 |
direct
|
| 510I | PLATRNR[T/I]TSVDFKDT | 0 |
direct
|
| 512L | PLATRNRTS[V/L]VDFKDT | 2 |
proximal
|
| 509C | PLATRN[R/C]RTSVDFKDT | 1 |
proximal
|
PTM Site: 511S
Affected site:
Position: 511
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 510P | LATRNR[T/P]TSVDFKDTD | 1 |
proximal
|
| 510I | LATRNR[T/I]TSVDFKDTD | 1 |
proximal
|
| 512L | LATRNRTS[V/L]VDFKDTD | 1 |
proximal
|
| 509C | LATRN[R/C]RTSVDFKDTD | 2 |
network-rewiring
|
PTM Site: 515K
Affected site:
Position: 515
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 510P | NR[T/P]TSVDFKDTDYKRH | 5 |
distal
|
| 510I | NR[T/I]TSVDFKDTDYKRH | 5 |
distal
|
| 512L | NRTS[V/L]VDFKDTDYKRH | 3 |
distal
|
| 509C | N[R/C]RTSVDFKDTDYKRH | 6 |
distal
|
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