ACAP2 V580L

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Mutation:

Summary

Isoform:

NM_012287

Position:

580

Ref:

Mutation:

PTM impact:

proximal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

HNSC

Cancer types: (PCAWG)

Head-SCC

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 581S

Affected site:

Position: 581

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
579M	ESLPS[T/M]TVSANSLYEP	2	proximal
583S	ESLPSTVSA[N/S]NSLYEP	2	proximal
575P	E[S/P]SLPSTVSANSLYEP	6	distal
577T	ESL[P/T]PSTVSANSLYEP	4	distal
580L	ESLPST[V/L]VSANSLYEP	1	proximal

PTM Site: 584S

Affected site:

Position: 584

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
579M	PS[T/M]TVSANSLYEPEGE	5	distal
583S	PSTVSA[N/S]NSLYEPEGE	1	proximal
580L	PST[V/L]VSANSLYEPEGE	4	distal

PTM Site: 586Y

Affected site:

Position: 586

Residue: Y

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
591K	TVSANSLYEPEG[E/K]ERQ	5	distal
583S	TVSA[N/S]NSLYEPEGERQ	3	distal
580L	T[V/L]VSANSLYEPEGERQ	6	distal

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