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Mutation:
ANKRD11 P277L
Summary
Isoform:
Position:
277
Ref:
P
Mutation:
L
PTM impact:
network-rewiring
PTM affected:
1
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
LUAD, STAD
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 276S
Affected site:
Position: 276
Residue: S
Type: phosphorylation
Best loss of PTM site:
MAPK1 (probability p=0.948)
Site: 276S (phosphorylation)
Position in motif: 1
There are 5 other predicted
losses:
- MAPK3 (p=0.906)
- MAPK14 (p=0.906)
- CDK2 (p=0.888)
- CDK7 (p=0.865)
- GSK3B (p=0.851)
Other known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 280L | TPLKVANSPTM[V/L]VNLL | 4 |
distal
|
| 275S | TPLKVA[N/S]NSPTMVNLL | 1 |
proximal
|
| 277L | TPLKVANS[P/L]PTMVNLL | 1 |
network-rewiring
|
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