After several years of serving the research community, our ActiveDriverDB database will be retired on May 1st 2026. Please make sure to download any data you need and update your links or workflows before that date.
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For any questions or assistance, please contact Jüri Reimand (juri.reimand@utoronto.ca).
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Mutation:
YTHDF1 G342R
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 346S
Affected site:
Position: 346
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 352R | GQSGGAGSDSNSP[G/R]GN | 6 |
distal
|
| 344S | GQSGG[A/S]AGSDSNSPGN | 2 |
proximal
|
| 350T | GQSGGAGSDSN[S/T]SPGN | 4 |
distal
|
| 348G | GQSGGAGSD[S/G]SNSPGN | 2 |
proximal
|
| 343V | GQSG[G/V]GAGSDSNSPGN | 3 |
distal
|
| 342R | GQS[G/R]GGAGSDSNSPGN | 4 |
distal
|
PTM Site: 348S
Affected site:
Position: 348
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 352R | SGGAGSDSNSP[G/R]GNVQ | 4 |
distal
|
| 344S | SGG[A/S]AGSDSNSPGNVQ | 4 |
distal
|
| 350T | SGGAGSDSN[S/T]SPGNVQ | 2 |
proximal
|
| 348G | SGGAGSD[S/G]SNSPGNVQ | 0 |
direct
|
| 343V | SG[G/V]GAGSDSNSPGNVQ | 5 |
distal
|
| 342R | S[G/R]GGAGSDSNSPGNVQ | 6 |
distal
|
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