You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020
Mutation:
ANKIB1 M923R
Summary
Isoform:
Position:
923
Ref:
M
Mutation:
R
PTM impact:
network-rewiring
PTM affected:
1
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
ACC
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 921S
Affected site:
Position: 921
Residue: S
Type: phosphorylation
Best gain of PTM site:
PRKCA (probability p=0.97)
Site: 921S (phosphorylation)
Position in motif: 2
There is 1 other predicted
gain:
- PRKCB (p=0.913)
Other known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 918H | ELLE[L/H]LGDSLMRLGAE | 3 |
distal
|
| 916V | EL[L/V]LELGDSLMRLGAE | 5 |
distal
|
| 923R | ELLELGDSL[M/R]MRLGAE | 2 |
network-rewiring
|
If you have any questions or feedback about this mutation:
Contact us