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Mutation:
FGA K249N
Summary
Isoform:
Position:
249
Ref:
K
Mutation:
N
PTM impact:
network-rewiring
PTM affected:
1
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
LIHC
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 252T
Affected site:
Position: 252
Residue: T
Type: O-glycosylation, phosphorylation
Only loss of PTM site:
PAK1 (probability p=0.872)
Site: 252T (phosphorylation, O-glycosylation)
Position in motif: -3
Other known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 254T | PPEWKALTD[M/T]MPQMRM | 2 |
proximal
|
| 248C | PPE[W/C]WKALTDMPQMRM | 4 |
distal
|
| 249N | PPEW[K/N]KALTDMPQMRM | 3 |
network-rewiring
|
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