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Mutation:
CDC73 A184P
Summary
Clinical Information
Cancer types: (TCGA MC3)
LGG
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 178S
Affected site:
Position: 178
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 177V | RSLSEA[M/V]MSVEKIAAI | 1 |
proximal
|
| 172F | R[S/F]SLSEAMSVEKIAAI | 6 |
distal
|
| 177T | RSLSEA[M/T]MSVEKIAAI | 1 |
proximal
|
| 184P | RSLSEAMSVEKIA[A/P]AI | 6 |
distal
|
PTM Site: 181K
Affected site:
Position: 181
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 186E | SEAMSVEKIAAI[K/E]KAK | 5 |
distal
|
| 177V | SEA[M/V]MSVEKIAAIKAK | 4 |
distal
|
| 177T | SEA[M/T]MSVEKIAAIKAK | 4 |
distal
|
| 184P | SEAMSVEKIA[A/P]AIKAK | 3 |
distal
|
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