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Mutation:
ZRANB3 T575M
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0082]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 569S
Affected site:
Position: 569
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 575M | RDIIDYESDVEPE[T/M]TK | 6 |
distal
|
| 573S | RDIIDYESDVE[P/S]PETK | 4 |
distal
|
| 566N | RDII[D/N]DYESDVEPETK | 3 |
distal
|
| 564S | RD[I/S]IIDYESDVEPETK | 5 |
distal
|
| 563G | R[D/G]DIIDYESDVEPETK | 6 |
distal
|
| 574K | RDIIDYESDVEP[E/K]ETK | 5 |
distal
|
PTM Site: 575T
Affected site:
Position: 575
Residue: T
Type: phosphorylation
Impact:
directOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 575M | ESDVEPE[T/M]TKRLKLAA | 0 |
direct
|
| 573S | ESDVE[P/S]PETKRLKLAA | 2 |
proximal
|
| 574K | ESDVEP[E/K]ETKRLKLAA | 1 |
proximal
|
PTM Site: 579K
Affected site:
Position: 579
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 575M | EPE[T/M]TKRLKLAASEDH | 4 |
distal
|
| 573S | E[P/S]PETKRLKLAASEDH | 6 |
distal
|
| 585Y | EPETKRLKLAASE[D/Y]DH | 6 |
distal
|
| 583L | EPETKRLKLAA[S/L]SEDH | 4 |
distal
|
| 574K | EP[E/K]ETKRLKLAASEDH | 5 |
distal
|
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