You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020
Mutation:
RAD51D M180I
Summary
Clinical Information
Cancer types: (TCGA MC3)
STAD
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer, familial 4
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 185K
Affected site:
Position: 185
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 191I | RRMACLAKSSRQP[T/I]TG | 6 |
distal
|
| 191R | RRMACLAKSSRQP[T/R]TG | 6 |
distal
|
| 191A | RRMACLAKSSRQP[T/A]TG | 6 |
distal
|
| 190L | RRMACLAKSSRQ[P/L]PTG | 5 |
distal
|
| 188Q | RRMACLAKSS[R/Q]RQPTG | 3 |
distal
|
| 187F | RRMACLAKS[S/F]SRQPTG | 2 |
proximal
|
| 186F | RRMACLAK[S/F]SSRQPTG | 1 |
proximal
|
| 185Q | RRMACLA[K/Q]KSSRQPTG | 0 |
direct
|
| 184S | RRMACL[A/S]AKSSRQPTG | 1 |
proximal
|
| 183V | RRMAC[L/V]LAKSSRQPTG | 2 |
proximal
|
| 182Y | RRMA[C/Y]CLAKSSRQPTG | 3 |
distal
|
| 181V | RRM[A/V]ACLAKSSRQPTG | 4 |
distal
|
| 181E | RRM[A/E]ACLAKSSRQPTG | 4 |
distal
|
| 181T | RRM[A/T]ACLAKSSRQPTG | 4 |
distal
|
| 180I | RR[M/I]MACLAKSSRQPTG | 5 |
distal
|
| 180V | RR[M/V]MACLAKSSRQPTG | 5 |
distal
|
| 179H | R[R/H]RMACLAKSSRQPTG | 6 |
distal
|
| 179C | R[R/C]RMACLAKSSRQPTG | 6 |
distal
|
| 179S | R[R/S]RMACLAKSSRQPTG | 6 |
distal
|
If you have any questions or feedback about this mutation:
Contact us