ANXA11 L258V

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Mutation:

Summary

Isoform:

NM_145869

Position:

258

Ref:

Mutation:

PTM impact:

proximal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

[0.0077]

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 252K

Affected site:

Position: 252

Residue: K

Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
258V	AYGKDLIKDLKSE[L/V]LS	6	distal
249G	AYGK[D/G]DLIKDLKSELS	3	distal
256F	AYGKDLIKDLK[S/F]SELS	4	distal
247S	AY[G/S]GKDLIKDLKSELS	5	distal

PTM Site: 255K

Affected site:

Position: 255

Residue: K

Type: sumoylation, acetylation, ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
258V	KDLIKDLKSE[L/V]LSGNF	3	distal
249G	K[D/G]DLIKDLKSELSGNF	6	distal
256F	KDLIKDLK[S/F]SELSGNF	1	proximal

PTM Site: 259S

Affected site:

Position: 259

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
258V	KDLKSE[L/V]LSGNFEKTI	1	proximal
256F	KDLK[S/F]SELSGNFEKTI	3	distal

PTM Site: 264K

Affected site:

Position: 264

Residue: K

Type: methylation, ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
258V	E[L/V]LSGNFEKTILALMK	6	distal
268V	ELSGNFEKTIL[A/V]ALMK	4	distal

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