You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020
Mutation:
MINK1 R768C
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 763S
Affected site:
Position: 763
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 768L | GHLPQAGSLERN[R/L]RVG | 5 |
distal
|
| 769M | GHLPQAGSLERNR[V/M]VG | 6 |
distal
|
| 768C | GHLPQAGSLERN[R/C]RVG | 5 |
distal
|
PTM Site: 772S
Affected site:
Position: 772
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 768L | ERN[R/L]RVGVSSKPDSSP | 4 |
distal
|
| 769M | ERNR[V/M]VGVSSKPDSSP | 3 |
distal
|
| 771A | ERNRVG[V/A]VSSKPDSSP | 1 |
proximal
|
| 775L | ERNRVGVSSK[P/L]PDSSP | 3 |
distal
|
| 768C | ERN[R/C]RVGVSSKPDSSP | 4 |
distal
|
If you have any questions or feedback about this mutation:
Contact us