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PDE4C (NM_001098818) - phosphodiesterase 4C

Camp-Specific 3',5'-Cyclic Phosphodiesterase 4c Isoform 3

PTM Interaction Network Visualisation

Protein summary

This is an alternative isoform of PDE4C protein. View all 3 isoforms
PDE4C: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform 3
Description:

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].

Strand
-
Chromosome
19
Protein
680 residues
All mutations
126
PTM sites
9
CDS
18,321,738 - 18,337,225
Transcription
18,318,770 - 18,337,285
35.88% of sequence is predicted to be disordered

Usage summary

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External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 5143
UniProt
Ensembl