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BRPF1 (NM_004634) - bromodomain and PHD finger containing 1

Peregrin Isoform 2

PTM Interaction Network Visualisation

Protein summary

This is preferred isoform of BRPF1 protein. View all 2 isoforms
BRPF1: peregrin isoform 2
Description:

This gene encodes a bromodomain, PHD finger and chromo/Tudor-related Pro-Trp-Trp-Pro (PWWP) domain containing protein. The encoded protein is a component of the MOZ/MORF histone acetyltransferase complexes which function as a transcriptional regulators. This protein binds to the catalytic MYST domains of the MOZ and MORF proteins and may play a role in stimulating acetyltransferase and transcriptional activity of the complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].

Strand
+
Chromosome
3
Protein
1214 residues
All mutations
159
PTM sites
43
CDS
9,775,824 - 9,789,033
Transcription
9,773,433 - 9,789,699
47.36% of sequence is predicted to be disordered

Usage summary

Network

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PTM site

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Kinases group

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Kinase, PTM site or protein

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External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 7862
UniProt
Ensembl