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DAZAP2 (NM_001136264) - DAZ associated protein 2

Daz-Associated Protein 2 Isoform B

PTM Interaction Network Visualisation

Protein summary

This is an alternative isoform of DAZAP2 protein. View all 6 isoforms
DAZAP2: DAZ-associated protein 2 isoform b
Description:

This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

Strand
+
Chromosome
12
Protein
146 residues
All mutations
22
PTM sites
3
CDS
51,632,691 - 51,636,242
Transcription
51,632,507 - 51,637,717
52.05% of sequence is predicted to be disordered

Usage summary

Network

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PTM site

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Kinases group

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Kinase, PTM site or protein

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External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 9802
UniProt
Ensembl