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BRD7 (NM_001173984) - bromodomain containing 7

Bromodomain-Containing Protein 7 Isoform 1

PTM Interaction Network Visualisation

Protein summary

This is an alternative isoform of BRD7 protein. View all 2 isoforms
BRD7: bromodomain-containing protein 7 isoform 1
Description:

This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010].

Strand
-
Chromosome
16
Protein
652 residues
All mutations
97
PTM sites
27
CDS
50,353,121 - 50,402,685
Transcription
50,352,928 - 50,402,845
48.31% of sequence is predicted to be disordered

Usage summary

Network

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PTM site

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Kinases group

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Kinase, PTM site or protein

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External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 29117
UniProt
Ensembl