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RBBP7 (NM_001198719) - RB binding protein 7, chromatin remodeling factor

Histone-Binding Protein Rbbp7 Isoform 1

PTM Interaction Network Visualisation

Protein summary

This is an alternative isoform of RBBP7 protein. View all 2 isoforms
RBBP7: histone-binding protein RBBP7 isoform 1
Description:

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].

Strand
-
Chromosome
X
Protein
469 residues
All mutations
45
PTM sites
33
CDS
16,863,157 - 16,887,764
Transcription
16,862,774 - 16,887,978
17.91% of sequence is predicted to be disordered

Usage summary

Network

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Kinase, PTM site or protein

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External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 5931
UniProt
Ensembl