SMARCB1 (NM_003073) - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Swi/snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily B Member 1 Isoform A
Legend
Protein
Kinases
Sites
Color corresponds to (the most severe) impact of mutations on given site:
Interactions
If you have any questions or feedback about this protein:
Contact us
PTM Interaction Network Visualisation
Protein summary
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015].
- Strand
- +
- Chromosome
- 22
- Protein
- 385 residues
- All mutations
- 96
- PTM sites
- 14
- CDS
- 24,129,356 - 24,176,367
- Transcription
- 24,129,149 - 24,176,705
Usage summary
Network
PTM site
Kinases group
|
Kinase, PTM site or protein
|