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TP53BP2 (NM_005426) - tumor protein p53 binding protein 2

Apoptosis-Stimulating Of P53 Protein 2 Isoform 2

PTM Interaction Network Visualisation

Protein summary

This is an alternative isoform of TP53BP2 protein. View all 2 isoforms
TP53BP2: apoptosis-stimulating of p53 protein 2 isoform 2
Description:

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Strand
-
Chromosome
1
Protein
1005 residues
All mutations
161
PTM sites
11
CDS
223,968,554 - 223,994,634
Transcription
223,967,594 - 224,033,674
68.76% of sequence is predicted to be disordered

Usage summary

Network

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PTM site

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Kinases group

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Kinase, PTM site or protein

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External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 7159
UniProt
Ensembl