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EHMT2 (NM_006709) - euchromatic histone lysine methyltransferase 2

Histone-Lysine N-Methyltransferase Ehmt2 Isoform A

PTM Interaction Network Visualisation

Protein summary

This is preferred isoform of EHMT2 protein. View all 2 isoforms
EHMT2: histone-lysine N-methyltransferase EHMT2 isoform a
Description:

This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].

Strand
-
Chromosome
6
Protein
1210 residues
All mutations
158
PTM sites
54
CDS
31,847,860 - 31,865,454
Transcription
31,847,535 - 31,865,484
43.88% of sequence is predicted to be disordered

Usage summary

Network

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PTM site

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Kinases group

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Kinase, PTM site or protein

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External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 10919
UniProt
Ensembl