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PPP2CA (NM_002715) - protein phosphatase 2 catalytic subunit alpha

Serine/threonine-Protein Phosphatase 2a Catalytic Subunit Alpha Isoform Isoform 1

Mutations Visualisation

Protein summary

This is preferred isoform of PPP2CA protein.
PPP2CA: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform 1
Description:

This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008].

Strand
-
Chromosome
5
Protein
309 residues
All mutations
30
PTM sites
20
CDS
133,533,462 - 133,561,552
Transcription
133,532,147 - 133,561,950
6.8% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 5515
UniProt
Ensembl